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Domestic Programs

The CFAR Programs are organized by the diverse expertise and experience of our faculty; many of whose investigations span across several Programs. The research evolves as new ideas, talent and discoveries emerge.

Research Program
Description
Program Director
Developmental Therapeutics This Program is focused on the development and evaluation of new drugs and treatment strategies to combat HIV disease, and finding simpler regimens with less complications for those with HIV. Investigators also study the pathogenesis of HIV disease in vivo by using therapeutic interventions that suppress HIV replication or initiate anti-HIV immune responses. The Program includes studies supported by the Adult and Pediatric AIDS CLinical Trials Units, the AIDS Malignancy Consortium (AMC), Studies of OCular Complications with AIDS (SOCA) and the NIDA-funded Clinical Trials Node. Fred Valentine, M.D.
Viral Pathogenesis This Program aims to conduct studies to determine the cellular pathways of HIV entry and replication, both in vitro and in vivo, and to detemrine the effects of this replication on the immune system DanLittman, M.D., Ph.D.
HIV-Associated Diseases This Program investigates the basic and clinical aspects of infections and complications of HIV disease including: tuberculosis and pneumocystic carinii, ocular complications, such as CMV, and AIDS-related malignancies. The Program focuses on the diagnosis and treatment of such complications, both locally and abroad. William Rom, M.D., MPH
Pediatric HIV Disease This Program focuses on the transmission, pathogenesis, and treatment of HIV disease in children and adolescents. It includes studies to prevent maternal-to-child transmission, both locally and abroad. William Borkowsky, M.D.
Epidemiology, Transmission and Prevention This Program aims to study the epidemiology and transmission of HIV and associated diseases, including hepatitis, syphillis, and tuberculosis, locally and abroad. These investigations help to develop intervention strategies for HIV prevention, including the feasibility of clinical trials of preventive vaccines. Michael Marmor, Ph.D.